The Hepato-Exposome Axis: How Endocrine Disruptors Hijack Liver Receptors to Drive MASLD
M. Martín-Grau, J.H. Kamstra, T. Hyötyläinen, M. Orešič, You Song, N. Veličković, A. Djordjevic, D. Vojnović Milutinović, R.F. Jackson, R. van Vorstenbosch
Vitenskapelig artikkel
2026 | Journal of Hepatology
Critical review of in vitro dosing methods for difficult-to-test substances and hydrocarbon UVCBs
Aina C Wennberg, Heidi Birch, Maria Christou, Sandrine E Deglin, Anastasia Georgantzopoulou, Maria Thérése Hultman, Neslihan Aygun Kocabas, Julie Krzykwa, Delina Y Lyon, Sophie Mentzel
Vitenskapelig oversiktsartikkel
2026 | Environmental Toxicology and Chemistry
Report on the 5th and 6th Mystery of Reactive Oxygen Species Conferences
Shihori Tanabe, Danielle Beaton, Richard A. Becker, Vinita Chauhan, Judy Choi, Eugene Choi, Alexander Cole, Marcus S. Cooke, Lucia Coppola, Maranda Esterhuizen
Journal Letter
2026 | ALTEX - Alternatives to Animal Experimentation
Adverse Outcome Pathway (AOP) Coaching Program—how it functions and contributes to a more harmonized approach to AOP development and construction of AOP networks with regulatory utility
Shihori Tanabe, Tanja Burgdorf, Judy Choi, Nathalie Delrue, Stephen W Edwards, Julija Filipovska, Rex FitzGerald, Sabina Halappanavar, Virginia K Hench, Travis Karschnik
Vitenskapelig artikkel
2025 | Environmental Toxicology and Chemistry
Critical review of in vitro dosing methods for hydrocarbon UVCBs
Aina Charlotte Wennberg, Adam David Lillicrap, Maria Thérése Hultman, Anastasia Georgantzopoulou, Maria Christou, You Song, Sophie Mentzel, Sandrine Deglin, Julie Krzykwa, Michelle Embry
Foredrag
2025 | SETAC Europe 35th Annual Meeting
Next Generation Risk Assessment of Emerging PFOA Alternatives Using Integrated New Approach Methodologies
You Song, Xueqi Fan, Maria Thérése Hultman, Maria Christou, Thomas Rundberget, Camden K. Klefbom, Yan Lin, Yangzhao Sun, Jun Huang, Li Xie
Vitenskapelig artikkel
2025 | Environmental Science and Technology
Comprehensive Characterization of RainbowTrout Hepatic 3D Spheroids Using Microscopyand a Multimode Detection Platform
Prem Chand, Tania Gomes, You Song, Anastasia Georgantzopoulou, Awadesh Jha, Coen Campsteijn, Maria Thérése Hultman
Konferanseplakat
2025 | Bridging Nordic Microscopy Infrastructure
Comprehensive Characterization of Rainbow Trout Hepatic 3D Spheroids: Morphological and Transcriptional Insights
Maria Thérése Hultman, Prem Chand, Tania Gomes, You Song, Anastasia Georgantzopoulou, Coen Campsteijn, Awadesh Jha
Konferanseplakat
2025 | The Society of Environmental Toxicology and Chemistry (SETAC)
Linking chemical disruption of molting processes to reduced survival of crustaceans
Knut-Erik Tollefsen, Bjørn Henrik Hansen, Simon Schmid, You Song, Celine Våga, Li Xie
Konferanseforedrag
2024 | Annual meeting in Norwegian Society for Pharmacology and Toxicology (NSFT)
A quantitative adverse outcome pathway (qAOP) linking mitochondrial uncoupling to growth inhibition in Lemna minor
Li Xie, Yang Cao, Solveig Jannicke Moe, Jan Thomas Rundberget, Maria Thérése Hultman, Knut Asbj�rn Solhaug, You Song
Konferanseforedrag
2024 | SETAC Europe 34th Annual Meeting
In silico and in vitro prioritization of emerging PFASs identified by non-targeted analysis for environmental hazard assessment
Xueqi Fan, Maria Thérése Hultman, Li Xie, Maria Christou, Jan Thomas Rundberget, Jun Huang, You Song
Konferanseforedrag
2024 | SETAC Europe 34th Annual Meeting
Can New Approach Methodologies (NAM) & Quantitative Adverse Outcome Pathways (qAOP) Replace Future Fish Toxicity Testing?
You Song, Yang Cao, Solveig Jannicke Moe, Prem Chand, Maria Christou, Jan Thomas Rundberget, Hongling Liu, Maria Thérése Hultman
Konferanseforedrag
2024 | SETAC Asia-Pacific 14th Biennial Meeting
Linking chemical disruption of molting processes to reduced survival of crustaceans
Knut-Erik Tollefsen, Bjørn Henrik Hansen, Simon Schmid, You Song, Celine Våga, Li Xie
Konferanseforedrag
2024 | Annual meeting in Norwegian Society for Pharmacology and Toxicology (NSFT)
Enhanced identification of endocrine disruptors through integration of science-based regulatory practices and innovative methodologies: The MERLON Project
Terje Svingen, Anna-Maria Andersson, Julianna Angelova, Marta Axelstad, Julie Bakker, Lisa Baumann, Anna Beronius, Nora Bouftas, Frederic Chalmel, Sofie Christiansen
Vitenskapelig artikkel
2024 | Open Research Europe
Report of the 3rd and 4th Mystery of Reactive Oxygen Species Conference
Shihori Tanabe, Danielle Beaton, Vinita Chauhan, Ian Choi, Judy Choi, Laure-Alix Clerbaux, Lucia Coppola, Antonio Fernandez Dumont, Maranda Esterhuizen, Julija Filipovska
Journal Leader
2023 | ALTEX - Alternatives to Animal Experimentation
Ciona spp. and ascidians as bioindicator organisms for evaluating effects of endocrine disrupting chemicals: A discussion paper
Jonny Beyer, You Song, Adam David Lillicrap, Simon Andres Rodriguez Satizabal, Marios Chatzigeorgiou
Vitenskapelig oversiktsartikkel
2023 | Marine Environmental Research
New Approach Methodologies for the Endocrine Activity Toolbox: Environmental Assessment for Fish and Amphibians
Constance A. Mitchell, Natalie Burden, Mark Bonnell, Markus Hecker, Thomas H. Hutchinson, Magdalena Jagla, Carlie A. LaLone, Laurent Lagadic, Scott G. Lynn, Bryon Shore
Vitenskapelig oversiktsartikkel
2023 | Environmental Toxicology and Chemistry
Multiomics Point of Departure (moPOD) Modeling Supports an Adverse Outcome Pathway Network for Ionizing Radiation
You Song, Keke Zheng, Dag Anders Brede, Tania Gomes, Li Xie, Yetneberk Ayalew Kassaye, Brit Salbu, Knut-Erik Tollefsen
Vitenskapelig artikkel
2023 | Environmental Science and Technology
Hepatic 3D Spheroids: The Next Generation of Testing in Toxicology (SPHERTOX)
Prem Chand, Tania Gomes, Karina Petersen, You Song, Heike Laue, Awadesh N. Jha, Nic Bury, Christer Hogstrand, Mikkel Elle Lepperød, Maria Thérése Hultman
Konferanseplakat
2022 | 32nd Society of Environmental Toxicology and Chemistry
Ultraviolet B modulates gamma radiation-induced stress responses in Lemna minor at multiple levels of biological organisation
Li Xie, You Song, Karina Petersen, Knut Asbjørn Solhaug, Ole Christian Lind, Dag Anders Brede, Brit Salbu, Knut-Erik Tollefsen
Vitenskapelig artikkel
2022 | Science of the Total Environment
Toward a consensus Adverse Outcome Pathways (AOP) network for radiation-induced reproductive effects in environmental species
Knut-Erik Tollefsen, Frederic Alonzo, Nicholas Beresford, Dag Anders Brede, Elizabeth Dufourcq-Sekatcheff, Rodolphe Gilbin, Nele Horemans, Selma Hurem, Patrick Laloi, Erica Maremonti
Konferanseforedrag
2022 | European Radiation Protection Week (ERPW)
Development and assessment of Adverse Outcome Pathways for juvenile hormone mediated effects of environmental stimuli and chemicals in cladocerans
Haruna Watanabe, Kenji Toyota, Hisashi Hirano, R. Abel, Hitoshi Miyakawa, You Song, Knut-Erik Tollefsen, Y. Yamada, H. Yamamoto, Taisen Iguchi
Konferanseplakat
2022 | 24th. Annual SETAC-North America meeting
Quantitative Adverse Outcome Pathways Assisted Next Generation Risk Assessment of Mitochondrial Toxicants
You Song, Adam David Lillicrap, Camila Vicencio Esguerra, Daniel L. Villeneuve, Daniel Ng, Jan Thomas Rundberget, Jannicke Moe, Jorke Harmen Kamstra, Knut-Erik Tollefsen, Li Xie
Konferanseforedrag
2022 | SETAC Asia-Pacific Annual Meeting 2022
In silico and experimental screening platform for characterizing environmental impact of industrial development in the Arctic – an overview of the project EXPECT
Samantha Eslava Martins, Gary S. Caldwell, Ian Edhlund, Anita Evenset, Tania Gomes, Bjørn Henrik Hansen, Gro Harlaug Refseth, Maria Thérése Hultman, Adam Jarvis, Maxim Kapralov
Konferanseplakat
2022 | 9th. Norwegian Environmental Toxicology Symposium (NETS)
Cumulative hazard and risk assessment of multiple stressor
Knut-Erik Tollefsen, Justin Brown, Gary S. Caldwell, Chloe Eastabrook, Emil Jarosz, You Song, Lindis Skipperud, Hans-Christian Teien, Li Xie
Konferanseforedrag
2022 | 5th International Conference on Radioecology & Environmental Radioactivity (ICRER)
The ecotoxicology of marine tributyltin (TBT) hotspots: A review
Jonny Beyer, You Song, Knut-Erik Tollefsen, John Arthur Berge, Lise Ann Tveiten, Aud Helland, Sigurd Øxnevad, Merete Schøyen
Vitenskapelig oversiktsartikkel
2022 | Marine Environmental Research
In silico and experimental screening platform for characterizing environmental impact of industrial development in the Arctic – an overview of the project EXPECT
Samantha Eslava Martins, Gary S. Caldwell, Ian Edhlund, Anita Evenset, Tania Gomes, Bjørn Henrik Hansen, Gro Harlaug Refseth, Maria Thérése Hultman, Adam Jarvis, Maxim Kapralov
Konferanseplakat
2022 | SETAC Europe 32nd Annual Meeting
In silico and experimental screening platform for characterizing environmental impact of industrial development in the Arctic – an overview of the project EXPECT
Samantha Eslava Martins, Gary S. Caldwell, Ian Edhlund, Anita Evenset, Tania Gomes, Bjørn Henrik Hansen, Gro Harlaug Refseth, Maria Thérése Hultman, Adam Jarvis, Maxim Kapralov
Konferanseplakat
2022 | Pollutant Responses In Marine Organisms" (PRIMO22)
Integrated exposure and hazard assessment of three trace metals on a marine copepod Tisbe battagliai
Chloe Eastabrook, Emil Jarosz, Li Xie, You Song, Gary S. Caldwell, Hans-Christian Teien, Knut-Erik Tollefsen
Konferanseforedrag
2022 | SETAC Europe 32nd Annual Meeting
Development of consensus AOPs for radiation-induced reproductive effects
Knut-Erik Tollefsen, Frederic Alonzo, Nicholas Beresford, Dag Anders Brede, Elizabeth Dufourcq-Sekatcheff, Rodolphe Gilbin, Nele Horemans, Selma Hurem, Patrick Laloi, Erica Maremonti
Konferanseforedrag
2022 | IDEA annual workshop
Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Knut Erik Tollefsen, Frederic Alonzo, Nicholas A. Beresford, Dag Anders Brede, Elizabeth Dufourcq-Sekatcheff, Rodolphe Gilbin, Nele Horemans, Selma Hurem, Patrick Laloi, Erica Maremonti
Vitenskapelig artikkel
2022 | International Journal of Radiation Biology
Development of consensus AOPs for radiation-induced reproductive effects
Knut-Erik Tollefsen, D.A. Brede, D. Oughton, E. Dufourcq-Sekatcheff, E. Maremonti, F. Alonzo, H. Zhu, N. Horemans, J.E. Olsen, M. Wood
Konferanseforedrag
2021 | European Radiation Protection Week 2021
Ultraviolet B Modulates Stress Responses of Lemna minor to Gamma Radiation at Multiple Levels of Biological Organization
Li Xie, You Song, Karina Petersen, Knut Asbjørn Solhaug, Ole Christian Lind, Dag Anders Brede, Brit Salbu, Knut-Erik Tollefsen
Konferanseplakat
2021 | SETAC Europe 2021 – SETAC Europe 31st Annual Meeting
Using Definitive Screening Design to Conduct Complex Experimental Testing of Chemical and Non-Chemical Mixtures
Chloe Eastabrook, Karina Petersen, Li Xie, You Song, Raoul Wolf, Gary S. Caldwell, Knut-Erik Tollefsen
Konferanseforedrag
2021 | SETAC Europe 2021 – SETAC Europe 31st Annual Meeting
High-throughput analyses and Bayesian network modeling highlight novel epigenetic Adverse Outcome Pathway networks of DNA methyltransferase inhibitor mediated transgenerational effects
You Song, Jorke H Kamstra, Yang Cao, Jana Asselman, Marc Anglès d'Auriac, Nikolai Friberg
Vitenskapelig artikkel
2021 | Journal of Hazardous Materials
Development of quantitative Adverse Outcome Pathways to facilitate next generation risk assessment of mitochondrial toxicants
You Song, Daniel L. Villeneuve, Jannicke Moe, Yang Cao, Maria Thérése Hultman, Maria Christou, Camila Vicencio Esguerra, Jan Thomas Rundberget, Li Xie, Adam David Lillicrap
Konferanseforedrag
2021 | SETAC North America 42nd Annual Meeting (SETAC SciCon4)
Adverse outcome pathway (AOP) guided high-throughput in vitro and in vivo assessment of mitochondrial toxicants.
Maria Thérése Hultman, Maria Christou, Jan Thomas Rundberget, Camila Vicencio Esguerra, Ian Edhlund, Jorke Kamstra, Adam David Lillicrap, You Song
Foredrag
2021 | SETAC North America 42nd Annual Meeting (SETAC SciCon4)
Adverse outcome pathway (AOP) guided high-throughput in vitro and in vivo assessment of mitochondrial toxicants
Maria Thérése Hultman, Maria Christou, Jan Thomas Rundberget, Camila Vicencio Esguerra, Ian Edhlund, Jorke Harmen Kamstra, Adam David Lillicrap, You Song
Konferanseforedrag
2021 | SETAC North America 42nd Annual Meeting (SETAC SciCon4)
Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development
Kenji Toyota, Haruna Watanabe, Masashi Hirano, Ryoko Abe, Hitoshi Miyakawa, You Song, Tomomi Sato, Shinichi Miyagawa, Knut Erik Tollefsen, Hiroshi Yamamoto
Vitenskapelig oversiktsartikkel
2021 | Aquatic Toxicology
Susceptibility of polar cod (Boreogadus saida) to a model carcinogen
Adélaïde Lerebours, Svetlana Murzina, You Song, Knut-Erik Tollefsen, Maura Benedetti, Francesco Regoli, Jeanette M. Rotchell, Jasmine Nahrgang
Vitenskapelig artikkel
2021 | Marine Environmental Research
Development of quantitative Adverse Outcome Pathways to facilitate next generation risk assessment of mitochondrial toxicants
You Song, Daniel Villeneuve, Jannicke Moe, Yang Cao, Maria Thérése Hultman, Maria Christou, Camila Vicencio Esguerra, Jan Thomas Rundberget, Li Xie, Adam David Lillicrap
Konferanseforedrag
2021 | SETAC North America 42nd Annual Meeting (SETAC SciCon4)
Development of consensus AOPs for radiation-induced reproductive effects
Knut-Erik Tollefsen, D.A. Brede, D. Oughton, E. Dufourcq-Sekatcheff, E. Maremonti, F. Alonzo, H.H. Zhu, N. Horemans, J.E. Olsen, L. Xie
Konferanseforedrag
2021 | International Dose Allicane (IDEA) workshop
Deciphering DNA methyltransferase inhibitor mediated transgenerational effects on Daphnia: high-throughput analyses and Adverse Outcome Pathway assembly
You Song, Jorke Harmen Kamstra, Yang Cao, Jana Asselman, Marc Anglès d'Auriac, Nikolai Friberg
Konferanseforedrag
2020 | SETAC Europe 30th Annual Meeting (SETAC SciCon)
The RiskAOP project - Quantitative Adverse Outcome Pathway assisted risk assessment of mitochondrial toxicants
You Song, Maria Thérése Hultman, Jannicke Moe, Karina Petersen, Jan Thomas Rundberget, Li Xie, Yang Cao, Camila Vicencio Esguerra, Riccardo De Bin, YeonKyeong Lee
Konferanseplakat
2020 | SETAC North America 41th Annual Meeting (SETAC SciCon2)
Multi-OMICS dose-response modeling reveals potential hazards of low-dose gamma radiation to Daphnia magna
You Song, Keke Zheng, Dag Anders Brede, Li Xie, Yetneberk Ayalew Kassaye, Brit Salbu, Knut-Erik Tollefsen
Konferanseforedrag
2020 | SETAC North America 41th Annual Meeting (SETAC SciCon2)
UV-B radiation modulates the effects of elevated gamma radiation in the aquatic macrophyte Lemna minor
Li Xie, Knut Asbjørn Solhaug, You Song, Dag Anders Brede, Ole Christian Lind, Brit Salbu, Knut-Erik Tollefsen
Konferanseplakat
2020 | SETAC Europe 30th Annual Meeting (SETAC SciCon)
Modes of action and adverse effects of gamma radiation in an aquatic macrophyte Lemna minor
Li Xie, Knut Asbjørn Solhaug, You Song, Dag Anders Brede, Ole Christian Lind, Brit Salbu, Knut-Erik Tollefsen
Konferanseplakat
2020 | SETAC Europe 30th Annual Meeting (SETAC SciCon)
Effects of artificial ultraviolet B radiation on the macrophyte Lemna minor: a conceptual study for toxicity pathway characterization
Li Xie, Knut Asbjørn Solhaug, You Song, Bjørn Johnsen, Jorunn Elisabeth Olsen, Knut-Erik Tollefsen
Konferanseplakat
2020 | SETAC Europe 30th Annual Meeting (SETAC SciCon)
Source to Outcome Pathways - a way forward in integrating marine exposure and impact assessment?
Chloe Eastabrook, You Song, Li Xie, Emil Jarosz, Raoul Wolf, Gary S. Caldwell, Hans-Christian Teien, Knut-Erik Tollefsen
Konferanseforedrag
2020 | SETAC Europe 30th Annual Meeting
Epigenetic, transcriptional and phenotypic responses in Daphnia magna exposed to low-level ionizing radiation
Jens Thaulow, You Song, Leif C Lindeman, Jorke H Kamstra, YeonKyeong Lee, Li Xie, Peter Alestrøm, Brit Salbu, Knut Erik Tollefsen
Vitenskapelig artikkel
2020 | Environmental Research
Cumulative Hazard and Risk Assessment of Pesticides from agricultural activities
Knut-Erik Tollefsen, Guri Sogn Andersen, Merete Grung, Marit Hauken, Sophie Mentzel, S. Jannicke Moe, Karina Petersen, You Song, Raoul Wolf, Li Xie
Konferanseplakat
2020 | SETAC Europe 30th Annual Meeting
Integrative assessment of low-dose gamma radiation effects on Daphnia magna reproduction: Toxicity pathway assembly and AOP development
You Song, Li Xie, YeonKyeong Lee, Dag Anders Brede, Fern Lyne, Yetneberk Kassaye, Jens Thaulow, Gary Caldwell, Brit Salbu, Knut Erik Tollefsen
Vitenskapelig artikkel
2020 | Science of the Total Environment
Daphnia as a model for understanding the sensitivity of aquatic organisms to chronic low-level ionizing radiation exposure
You Song, Keke Zheng, Li Xie, Chloe Eastabrook, Dag Anders Brede, Yetneberk Ayalew Kassaye, Tania Gomes, Gary S. Caldwell, Brit Salbu, Knut-Erik Tollefsen
Konferanseplakat
2020 | SETAC Europe 30th Annual Meeting